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The FDA announced the approval of a new weight reduction drug on Sept. 11, 2014. The drug name is Contrave.
Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it one should err on the side of caution and allow FDA do its job and demand some research be done so your public recognizes the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on their own medications.
Researchers found that participants using this drug for a year, dropped excess weight within one month and have kept the body weight off during the entire 56 weeks in the study. Contrave can be a combination from the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more potent and safer.
Combo-pilling will be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that by right now there aren't any long term prescription slimming capsules that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be licensed by the FDA.
Seizures certainly are a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise blood pressure and heart rate, and really should not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.
Suboxone consists of two drugs; buprenorphine and naloxone. The naloxone is irrelevant in the event the addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone may cause instant withdrawal. When suboxone is employed correctly, the naloxone is destroyed inside the liver shortly after uptake from the intestines and has no therapeutic effect. Buprenorphine may be the active substance; it can be absorbed beneath the tongue (and through the mouth) but destroyed with the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation if the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have also treated addicts who may have had gastric bypass, the location where the first section of the intestine is bypassed and also the stomach contents empty in to a more distal part of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy the place that the drug is taken up by the duodenum and transferred straight away to the liver through the portal vein, where it's quickly and completely destroyed. After gastric bypass naloxone can be taken on by servings of the intestine that are not served from the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.